
Rejuran at de Lune Aesthetics
Rejuvenate, regenerate, and repair your skin with Rejuran, a revolutionary treatment in bio-skin healing.Launched in Korea in 2014 and available in Australia since July 2023, Rejuran is a cutting-edge injectable treatment that uses Polynucleotides (PN) derived from wild salmon DNA.
This amazing technology is designed to stimulate skin regeneration, improve texture and elasticity, and reduce the appearance of fine lines, wrinkles, and scars—including acne scars.
What is Rejuran?
As we age, collagen production decreases, leading to wrinkles, sagging, and dull skin. Rejuran helps to restore this collagen production, boosting skin firmness, reducing the appearance of fine lines, and improving skin texture overall. Additionally, its anti-inflammatory effects support wound healing and scar remodelling.
Rejuran is an excellent addition to your skincare routine, offering long-term rejuvenation with minimal downtime.
How Does Rejuran Work?
After a thorough consultation to determine your suitability, a local anaesthetic is administered to help numb the area. Rejuran is then injected directly into the dermis in a series of injections using micro-fine needles.
Is it painful?
In most clinics, a topical anaesthetic such as EMLA is used before treatment to help manage discomfort, though the procedure is often still considered painful. At de Lune Aesthetics, our Rejuran treatments are administered by our founder, Plastic Surgeon Dr. Marion Chan, who ensures the area is completely numb using both a nerve block and a topical anaesthetic for a truly comfortable experience. While you may experience some mild redness or swelling post-treatment, most clients are able to resume their normal activities soon after.


Treatment Areas and Treatment Options
Rejuran can be used as a full-face treatment or to target specific areas, such as the cheeks, forehead, and under-eye area. It is also effective for spot-treating scars and uneven pigmentation.
Rejuran Treatment Options
Rejuran Classic: Ideal for full-face rejuvenation.
Rejuran-I: A targeted treatment for delicate areas such as the under-eye area.
Rejuran-S: Best for scar treatment and enhancing skin texture in problem areas.
Frequency of Treatments
Initial Phase: 3–4 sessions spaced 4 weeks apart to stimulate collagen production and improve skin texture.
Maintenance Phase: 1 session every 6–12 months to sustain results and maintain skin health.
FAQs
Find answers to your questions about Rejuran and enhance your understanding of this treatment.
A comprehensive medical consultation is carried out upon your arrival to ensure this is the appropriate treatment for you. Your face will be cleansed thoroughly, and formal clinical photographs taken which will form a part of your medical record and documentation. A topical anaesthetic cream is then applied to the areas being treated. Using micro-injections, Rejuran is administered carefully to the area with the aid of an additional local anaesthetic to ensure treatment is carried out as comfortably as possible, with minimal pain. A follow-up appointment will be made for you at 2 weeks. Procedure time: 30-60 mins (Total appointment time will be more due to consultation, photography, and preparation with anaesthetic cream)
Rejuran is an injectable which stimulates collagen production in the superficial layers of the skin. It is very different from products which provide facial volume and fullness.
Rejuran, bio-remodelling, and bio-stimulators are all injectable, but they differ in their composition, mechanisms of action, and intended outcomes.
Active skin conditions (eg. active infection), Pregnancy and breastfeeding, Autoimmune conditions, Chronic and significant medical conditions, Bleeding and coagulation disorders, Recent cosmetic treatments such as other injectables, laser or chemical peels and Unrealistic expectations
– Lumps or bumps which may look similar to mosquito bites. These usually resolve within 24-36 hours
– Bruising and swelling, usually resolves in 1-2 days
– Minor redness, injection marks and skin sensitivity, usually resolves in 1-3 days
– Scabs may form (uncommon), which will fall off within a few days.
Avoid high-temperature environments (eg. saunas and steam wounds) and strenuous exercise or activities which may increase blood flow to the treated area. Avoid active serums such as Vitamin A and C for 3 days. Excessive massage should be avoided. Sunscreen with a high SPF index is recommended to prevent pigmentation.
– Infection (rare), at injection sites, following our aftercare protocol is important to ensure this does not occur, Allergic reactions (rare) – it is important to alert us of any known allergies prior.
Rejuran can be administered to individuals with seafood or salmon allergies. The manufacturer’s proprietary technology results in extraction of pure polynucleotide that is free from allergenic protein components. No reported issues related to this have been reported over the past 10 years, with over 10 million syringes used.
Have Questions About Rejuran Treatments?
Reach out to the de Lune clinicians and we’ll happily discuss your questions or suitability for treatment.